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Hydrogels are three-dimensional cross-linked polymer networks that can absorb and retain a large amount of water or biological fluids
Since mammalian mPGES-2s have a defined role in prostanoid metabolism, all studies primarily investigated the PGH 2 conversion into PGE 2 (Watanabe et al., 1997)
animal reproduction studies show no embryotoxicity or teratogenicity at exposures up to eight times the maximum recommended human dose, yet placental transfer has been demonstrated in animal models, so human fetal risk cannot be ruled out
* Correspondence: Lorenzo Drago, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
