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Increased fission caused by the upregulation of proteins Fis1 and Drp1 normally promotes mitophagy [309]

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Moreover, in the NH 4 Cl-treated human astrocytes, increased concentration of 3-methyl-2-oxovaleric acid, which was ammonia induced and played a crucial role in neurological impairment, was significantly decreased with l-carnitine co-treatment

The major significance of type I hernias is in their association with reflux disease