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Retatrutide activates three hormone receptors (GLP-1, GIP, and glucagon) while tirzepatide activates two (GLP-1 and GIP)
You should contact your GP if natural approaches to improving metabolic health have not yielded results after 3-6 months, if you have been diagnosed with type 2 diabetes or non-diabetic hyperglycaemia (pre-diabetes, HbA1c 42-47 mmol/mol), if you are struggling with obesity-related health complications, or if you experience unexplained weight changes, persistent fatigue, or excessive thirst and urination
Liver injury has not been established as a common expected side effect of regulated retatrutide used in clinical trials
This helps reduce caloric intake so patients can lose weight
Discussing the cost and coverage of your GLP-1 medication with your healthcare provider will help you determine the best treatment option for your needs and budget
GLP-1 receptor agonists also slow gastric emptying, which moderates the postprandial glucose spike and promotes satiety through central nervous system pathways
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