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In rare cases, more severe side effects may occur

The GLP-1 weight loss medication market has expanded dramatically since semaglutide's clinical success in reducing body weight by up to 15% in large trials

Happy Ending I had hoped to be more positive in this article, but I think there are some nutritional issues worth highlighting

Further, higher baseline BMI and A1C may suggest that lower income individuals wait longer to add second line therapies, like GLP-1 RAs, potentially due to the high cost relative to first line therapies (such as metformin)

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I would say the biggest adjustment has been factored in, though some uncertainty remains