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In the pivotal Raun et al

Differences between inflammatory profiles within experimental groups were assessed using pairwise Wilcoxon tests with false discovery rate (FDR) correction

The new results echo a study published in February in the Journal of Clinical Endocrinology & Metabolism that linked GLP-1 drugs to a higher risk of osteoporosis-related fractures in older adults with Type 2 diabetes.

The combination addresses different metabolic constraints and is standard in medically-supervised protocols

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One explanation sometimes proposed for a raised HbA1c on a ketogenic diet is a metabolic adaptation variously described as 'adaptive glucose sparing' or 'physiological insulin resistance'