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Glutathione helps modulate inflammatory responses, potentially offering relief for those suffering from inflammation-related issues exacerbated by urban stressors

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During this process, oxygen is reduced to superoxide

Funding This work was supported by the National Natural Science Foundation of China (82374427 and 82260928)

NRF1 also controls the expression of nuclear genes required for mitochondrial respiration and heme biosynthesis

For most disease-modifying drugs, however, the adage no inflammation, little benefit remains largely true (Lublin et al., 2022)