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In a mouse model of type-2 diabetes, Sirt1 activation inhibited microglial activation by upregulating BDNF [35]
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Synthesis of ROS-sensitive polymers conjugated with Ru(II)-OH (P4) At room temperature, 4-Dimethylaminopyridine (DMAP, 126 mg) was introduced to a solution of Ru(II)-OH (50 mg) and 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDCl, 200 mg)
EMF interventions and therapeutic applications in prostate cancer In this perspective, we integrate recent advances through three interconnected axes that bridge biophysical mechanisms with oncological paradigms [Figure 1] and propose a reconciling framework for EMFs duality: (1) Calcium signaling as the central electromagnetic biosensor, where EMFs modulate ion flux to drive tumor aggressiveness or therapeutic vulnerability