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Future studies should also take into account the potential influence of gender on iron metabolism and its participation in PD pathogenesis and progression

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Accumulating evidence suggests that the regulation of ferroptosis can change the level of OS in cardiomyocytes or vascular cells, resulting in cardiomyocyte injury, cardiac hypertrophy and HF through the interaction between ROS with ERS ( In summary, CD is pivotal for internal homeostasis and prevention of CCVDs ( 3.3.4 Ferroptosis and Inflammation Inflammation is a basic pathological process including infection and tissue damage, and appears when the organism is stimulated by some specific physiological or pathological factors

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doi: 10.2337/diabetes.47.5.764 39 PaulyRPDemuthHURoscheFSchmidtJWhiteHALynnFet al