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Upregulation of sense gene via NAT degradation While the previously mentioned mechanisms function to upregulate the sense gene by directly acting upon the sense gene mRNA transcript, one limitation lies in the fact that uORFs only exist in approximately 50% of mammalian mRNA and within this 50%, not all are inhibitory [106, 107]

The scale of this phenomenon has grown from a fringe curiosity into a genuine public health concern

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Prediction of mortality and major adverse kidney events in critically ill patients with acute kidney injury

Several studies have reported that hydrophilic polymers form co-complexes with drugs and cyclodextrin and increase corneal drug adherence and flux through scleral tissue