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It successfully prevented obesity and insulin resistance in mice, but theres no human data, either for safety or effectiveness

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The problem is because theyre supplements, they dont undergo the same scrutiny by the FDA as medications. While many of these supplements claim to be clinically proven, are they really

The proportion of participants with prediabetes was 40.6% in SURMOUNT 1 34 while it was not reported in SURMOUNT 3 35 and 4 36 , enrolling patients with a mean HbA1c of 5.5%