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Real-time quantitative PCR was carried out on the CFX384 Touch Real-Time PCR Detection System (BIO-RAD)

Adverse events were primarily gastrointestinal, with nausea significantly more frequently in the GLP-1RAs group (OR = 2.01, 95% CI 1.24 to 3.27)

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the tirzepatide obesity trials measured it against placebo

Normally, plasma triglycerides are acted upon by lipoprotein lipase (LPL), an enzyme on the surface of the endothelial cells lining the vessels of adipose tissue, the heart, and skeletal muscle

Understanding the expected timeline for GLP-1 medication effects is essential for setting realistic expectations and avoiding premature discontinuation