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Cribb AE, Lee BL, Trepanier LA, Spielberg SP

Mutations in the genes encoding these proteins, as well as their abnormal expression, are associated with the pathogenesis of several diseases, including type 2 diabetes, insulin resistance, cancer, and neurodegenerative disorders

Increased motor drive and sleep loss in mice lacking Kv3-type potassium channels

For an additional insight into the mechanism of action, the tumorous tissue was stained with a ROS-specific dye and analyzed by CLSM

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November 22 Product: BridgeBios Attruby Indication: Transthyretin amyloid cardiomyopathy Thanksgiving came early for BridgeBioand transthyretin amyloid cardiomyopathy (ATTR-CM) patientsafter the FDA approved the companys Attruby a week before its scheduled PDUFA date