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Dihexa is a research peptide studied for its ability to activate growth-factor receptors in the brain, and clinicians explore it as one part of a supervised cognitive-health plan rather than a standalone fix

See Table 136 for a list of the final qualifying products for CY 2026, and please see Table 135 for a list of the final payment limitations for qualifying products for CY 2026

However, that level 5 APC payment weight would still continue to be primarily driven by the estimated costs of the currently assigned HCPCS code 33289 ( Transcatheter implantation of wireless pulmonary artery pressure sensor for long-term hemodynamic monitoring, including deployment and calibration of the sensor, right heart catheterization, selective pulmonary catheterization, radiological supervision and interpretation, and pulmonary artery angiography, when performed ), which has a geometric mean cost of $29,529.47

The compound showed an in vitro NNMT IC 50 of approximately 1.2 M and did not inhibit related methyltransferases at concentrations tested

Over 40 years of research and clinical use have established that it is well tolerated with minimal adverse effects at recommended doses

The latter could increase various biological pathways that encourage improved cognition