depression and tirzepatide GLP-1s linked to lower rates of anxiety than an older anti-obesity drug — not higher. #GLP1 #Semaglutide #Tirzepatide #ObesityMedicine #MentalHealth #Anxiety #Depression #Neuropsychiatry #ObesityTreatment #WeightManagement #Naltrexone Psychiatric Safety of Tirzepatide: 3

Los pacientes del brazo semaglutida continuaron perdiendo peso (hasta 13 kg ms de media) y en cambio los enfermos del grupo placebo comenzaron a ganar nuevamente peso, a pesar de todas las dietas hipocalricas (1200 kcal/da), el ejercicio fsico pautado y las visitas frecuentes al especialista (hasta 6,9 kg de ganancia media), tabla 1

Fix: Use for 46 weeks , then take 46 weeks off

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Oral therapies and off patent semaglutide will affect pricing and access, competition intensifies in an increasingly segmented market, and innovation shifts the focus beyond weight loss alone towards comorbidity benefit, long-term maintenance and muscle preservation

However, it is unknown if they are permanent, whether the organism may develop tolerance to the peptide, and what may happen to the results after stopping the treatment

In the SCALE study, liraglutide 3.0 mg daily showed reductions of systolic and diastolic blood pressure of 4.2 and 2.6 mmHg, respectively, and reductions in LDL-cholesterol and triglycerides of 3.0% and 13.3%, respectively, and increases in HDL-cholesterol of 2.3% [15]