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The compound remains in research status, lacking the clinical trial data required for regulatory approval

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Foretinib is a class II inhibitor targeting c-MET, VEGFR2, Recepteurd Origine Nantais (RON), kinase insert domain receptor (KDR), and Fms related tyrosine kinase 1 (Flt-1) with potent inhibition of c-MET kinase activity (enzymatic IC50 1.16 nM) [100]

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