Case reports were shared by some of the authors and discussed during the expert panel and reported in Supplementary Material
Patients should be counseled about these potential side effects before initiating therapy and instructed on appropriate management strategies and warning signs that warrant medical evaluation
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Vitamin D deficiency is associated with leptin resistance, which impairs the bodys ability to regulate hunger and fat storage
Deletions in PWS, particularly those affecting genes involved in neural development, brain function, infertility, and circadian rhythm, such as SNORD116, can result in proconvertase 1 deficiency leading to GHD, short stature, hypogonadism, hyperghrelinemia, relative hypoinsulinemia, and T2DM
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