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Well, if you're taking antioxidants, you do care about pro-oxidants

The current study makes a strong case for the plasma BDNF as a reliable non-invasive biomarker for the increase in brain omega-3 FA levels in response to treatments in patients

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Notably, at six months, mean GSH levels in erythrocytes, plasma, and lymphocytes had increased by 30-35% in the high-dose group, which was significantly greater than the increases observed in the placebo group

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Mitochondrial dysfunction, oxidative stress, inflammation, and impaired ATP production occur in a feedforward cycle, serving as both consequences and causes of the marked reduction in glucose metabolism in the brain across the spectrum of ADRD development (Wang et al., 2017)