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Titta, L., Trinei, M., Stendardo, M., Berniakovich, I., Petroni, K., Tonelli, C., Riso, P., Porrini, M., Minucci, S., Pelicci, P

Sustained weight loss in people with obesity is associated with improvements in health.1 3 Health behaviour changes alone generally achieve only a modest (3%5%) weight loss, which is usually not sustained over the long term and may not be sufficient to improve most adiposity-related complications.4 6 Along with psychological support and metabolic and bariatric surgery, and supported by medical nutritional therapy and physical activity, pharmacotherapy is one of the mainstays of obesity treatment

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