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There is no reason to combine these medications as they target the same receptor so you would just be engaging in overkill with no additional benefits However, there are times when you can add additional or stack peptides such as CJC 1295/Ipamorelin, AOD 9604, or MOTS-C, although these would need pre-approval from one of our medical providers How do I avoid GI (gastrointestinal) upset

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Microdosing involves starting and staying at much lower dosessometimes as low as 0.1 to 0.25 mg per week for semaglutide or even intermittent use

Study-related adverse events In a 26-week, open-label study in adult patients (N=665) comparing Victoza 1.2 mg, Victoza 1.8 mg, and sitagliptin 100 mg, all in combination with metformin, the adverse reactions reported in 5% of patients treated with Victoza were nausea (23.9% vs 4.6%), headache (10.3% vs 10.0%), diarrhea (9.3% vs 4.6%), and vomiting (8.7% vs 4.1%)