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Think of the bodys adjustment as a thermostat finding a new set point: it may overshoot, oscillate, and then settle

PMID: 32798065

Regular blood donation or therapeutic phlebotomy maintains safe levels

2014;348:g2366

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Appetite suppression itself is technically the desired effect, but many patients describe it as uncomfortable during adjustmentnot just reduced hunger, but a complete absence of food interest that can make mealtimes feel strange