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The underlying mechanism might be that reduced KCC2 and NKCC1 ratios lead to the relatively slow maturation of neural circuitry

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Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca(2+)

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Surgery becomes necessary only when conservative treatment fails after 6-12 weeks, you experience progressive leg weakness, or serious complications develop