Nat Rev Nephrol 16(1):5164
To qualify, you must have a documented diagnosis of type 2 diabetes and have previously tried other standard, first-line glucose-lowering medications without achieving your target A1C goals
Do not take the medication if you are under 18, pregnant or breastfeeding, and make sure you speak to your doctor about any other medical conditions you have or medication you take
Loomba R et al., SYNERGY-NASH, NEJM 2024 (NEJMoa2401943, PMID 38856224) : tirzepatide and MASH, resolution in 62% at the 15 mg level
The patient was recommended to continue with usual IC care, including avoiding dietary bladder irritants
Negative ion ultraviolet matrix-assisted laser desorption ionization mass spectrometry and post source decay of glycosyl esters of nucleoside pyrophosphates