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Eventually, some patients may taper off medication under medical guidance, while others continue long-term maintenance depending on individual progress

doi: 10.1038/ismej.2012.4 54 RussellWRGratzSWDuncanSHHoltropGInceJScobbieLet al

"At the moment, the larger conversation is not about doping it is about athlete health, body composition management, fueling, recovery and the long-term implications of using these medications in already high-performing individuals," Kovacs said

Yuan and a group of other researchers recently published a paper comparing the effectiveness of different GLP-1RAs

A 2026 analysis in the Journal of Medical Internet Research found real-world discontinuation rates far exceed clinical trial numbers, with up to 70% of patients stopping treatment within 24 months -- often because of these effects

The company claims the program can help you lose an average of 15% to 20% of your body weight within 12 months