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Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease

GLP-1R plays a significant role in the triad, making it an appealing target for treatment (Fig

Their dosing follows a fixed escalation schedule designed to minimize gastrointestinal side effects

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Animal studies Prokinetic activity of TZP-102 was evaluated in a rat model of gastric emptying, in which TZP-102 in a dose-dependent manner increased gastric emptying up to 51% in comparison to vehicle