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They enhance autophagy and reduce lipotoxicity-induced hepatocyte apoptosis, thereby preserving the integrity of liver parenchyma (12)

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Thus, once-weekly administration of semaglutide at a dose of 1.0 mg reduced the risk of heart failure events and CV death in a high-risk population comprising individuals with T2D and CKD, irrespective of their prior history of heart failure (88)

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