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Probably because the clinical trial grew directly out of Shungus successful NIH-funded ME/CFS research effort

Post-marketing surveillance has documented reports of such experiences

Montagne et al., 2022)

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In comparison, subcutaneously administered semaglutide given as a single injection (0.5 mg) has shown a C max of 10 nM with T max of 24 h with a similar 1-week half life [30]

While it has proven effective, patients may experience a range of side effects, both short-term and long-term