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For people with severe obesity, the ones the drug was actually built for, thats going to be a very big deal if the safety and durability data hold up: surgery-level weight loss from a weekly shot, under real medical supervision

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Plus, there is plenty of anecdotal evidence that the pill can fail while women are on GLP-1s, leading to so-called Ozempic babies

[13] Perhaps the most striking demonstration used an inulin-propionate ester a molecule designed to deliver propionate straight to the colon

Bot activity and speeders were identified, with minimal exclusions

It was pretty prohibitive