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DSS-induced colitis in mice elicited pronounced symptoms, including reduced locomotor activity, decreased consumption of food and water, dull and lifeless fur, signs of depression-like behavior, huddling behavior, perianal swelling and congestion, diarrhea, bloody stools, and substantial weight loss

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Its also worth noting that reaching the maintenance dose, which usually happens around 17 weeks, is when many people see the most substantial changes

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"Our data really shows that these behavioral changes persist over time, and the adoption curve resembles one of the fastest consumer disruptions on record," Furman told USA TODAY