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Hyperglycemia Diabetes is associated with the accelerated disappearance of capillary endothelium [159], morphological and functional alterations of ECs [160], and the weakening of intercellular junctions [161], which ultimately leads to ECD

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[2] [4] Injection site reactions may occur with subcutaneous GLP-1 formulations, presenting as redness, itching, or mild swelling at the injection site

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When that happens, you get more tired more easily, gain weight more easily, or recover more slowly