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To further confirm this result, we treated tendon fibroblasts with BPC 157 at different concentrations (0, 0.1, 0.25 and 0.5 g/mL) for 24 h and the expression of growth hormone receptor was found to increase in a dose-dependent manner (Figure 1A,C)

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The main precautionary note for GHK-Cu concerns individuals with known copper metabolism disorders or Wilsons disease, for whom any additional copper loading, including from GHK-Cu, would be contraindicated

by Irma Bernadette S

Its plasma concentration decreases with age: approximately 200 ng/ml at age 20 versus 80 ng/ml at age 60, correlating with the decline in regenerative capacity