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Studies indicate that long-term use of KD conditions vitamin C, biotin, and zinc deficiencies ( Vitamin C is an important antioxidant that plays a key role in collagen synthesis (241, 242)

The SHP2-ERK1/2 pathway also exhibits a neurotrophic function during the development of hypothalamic feeding circuits

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It is used clinically and in research for tissue repair, with studies covering tendon and ligament injury, muscle strain, gut lining damage (including ulcers and inflammatory bowel conditions), and post-surgical recovery

Yes, combining oral supplements with injections can enhance and maintain the skin lightening effects

These same comfort strategies apply to managing other tirzepatide-related discomfort that interferes with daily life