Cysteine and homocysteine metabolism are influenced by dietary factors, including the intake of methionine, vitamins (B6, B12, folate), and other nutrients
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Moreover, several GSH-responsive systems have progressed toward early-phase clinical evaluation Fig
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For the Sec-containing enzyme, the hydrogen bond distance between the Sec46 and the Gln81 of the catalytic site is much shorter, at 3.2