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Factors such as inflammation, reduced granulation tissue formation, neuropathy, and insufficient angiogenesis impede wound healing, and oxidative stress is a key pathogenic factor ( 2 ), activates pathways such as PKC, polyol, and hexosamine, and increases the formation of AGEs

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Marinov (MD, Ph.D.) is a researcher and chief assistant professor in Preventative Medicine & Public Health

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They are provided to help interpret the literature, not as a protocol for human use