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New research from Blue Cross Blue Shield reveals that, among 170,000 patients using a GLP-1 for weight management, 58% discontinued use before reaching a clinically meaningful health benefit

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In each patient, efforts were made to periodically reduce the dose of erythropoietin, but any reduction in the erythropoietin dose was maintained only if the hematocrit did not decrease

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It demonstrates that despite the sympathetic excitatory effect of GLP-1RA, GLP-1RA exhibits a degree of safety in terms of the risk of arrhythmia in patients with type 2 diabetes, with the implication that the use of GLP-1RA analogues may be considered to improve or maintain glucose-lowering therapy in patients with a long history of disease when clinically encountering patients with arrhythmias that meet the indications but for whom the use of SGLT2i is contraindicated