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Pros Cons Compounded version only available during FDA-confirmed shortages Compounded version must be drawn with syringe and injected manually Possible side effects: nausea, GI discomfort, headache, fatigue Not covered by insurance if compounded

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CagriSema is under FDA review with a decision expected by late 2026, and the RENEW program will give us a fuller picture of what cagrilintide can do as a standalone treatment