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While constipation on semaglutide is common and often manageable with over-the-counter interventions, certain clinical scenarios warrant prompt medical evaluation to exclude serious complications or underlying pathology

If you're actively trying to preserve or build muscle: you'll still want complete protein in your day (foods or whey/soy/pea blends), plus resistance training

If a gynecological issue is suspected, appropriate treatment can be initiated, or a referral to a gynecologist may be made for further evaluation

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This can increase the shelf life of the vials for months and potentially years