Recent studies on Long COVID and ME/CFS patients have revealed signs of elevated oxidative stress and aberrations in ROS clearance pathways, including elevated glutathione levels, decreases in mitochondrial superoxide dismutase, and lipid oxidative damage
At therapeutic doses, gut absorption becomes the limiting factor IV delivery removes that ceiling
Furthermore, the well documented efficacy of combined folic acid, B6, and B12-vitamin supplementation to reduce hyperhomocysteinemia could enhance GSH activity and reduce oxidative stress (161)
Highly stable and biocompatible hyaluronic acid-rehabilitated nanoscale MOF-Fe(2+) induced ferroptosis in breast cancer cells
For a broader overview of what a glutathione supplement is meant to do, see What Does a Glutathione Supplement Do
Maximum minoxidil results occur around 12 months, after which maintenance rather than continued improvement becomes the goal