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Two predicted drugs (gemcitabine and cladribine) and one NO-based drug (diphenyleneiodonium) have a reported median IC 50 below 0.4 M in melanoma cell lines, this being comparable to known anti-melanoma drugs (Supplementary Fig

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However, these results correlate with the increased bacterial control seen in mice treated with RIF and L-GSH compared to other treatment groups (Figure 10)