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As shown in Table 1, the enrollment was age- and sex-matched because there were no significant differences in age and gender distribution between the patients and the healthy control groups

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doi: 10.1016/j.tibs.2019.01.001 55 ZengQMaXSongYChenQJiao Q and ZhouL

KEGG pathway enrichment analysis statistically evaluates whether a set of genes or proteins is over-represented in specific pathways compared with a background distribution, highlighting biological systems significantly impacted under experimental conditions

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HIF-1: hypoxia inducible factor-1