Oxidative stress disturbs this balance, creating an unstable cellular environment that can damage DNA, proteins, and lipids, as well as cause inflammation and harm to renal epithelial cells (64)
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Regulation of Glutathione Synthesis
CYP24A1, a gene that provides instructions for making the enzyme 24-hydroxylase, is involved in the catabolism of both 25(OH)VD 3 and 1,25(OH) 2 D 3, thereby limiting vitamin D receptor (VDR)/1,25(OH) 2 D 3 signaling 14
Deficiency can lead to conditions like inflammation, cancer, diabetes, and neurodegenerative diseases
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