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For example, the compound 13 (racemic) is a very week IRAP inhibitor (Lukaszuk et al., 2011) and compound 14 with a 4-hydroxydiphenylmethane scaffold as a substitute for Tyr 2 is essentially inactive (Figure 4) (Andersson et al., 2008)

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However, upon termination of the medication and accompanying lifestyle modifications, by the 120-week mark (52 weeks post-discontinuation), participants were observed to have regained approximately two-thirds of the weight they had previously shed

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Evidence from clinical studies confirmed the protective role of statins against the development and progression of AD (Haag et al., 2009