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10.1016/j.ajo.2022.01.020 37 VanDerMeidK

Immune and inflammatory networks in myocardial infarction: current research and its potential implications for the clinic

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Overweight and obesity are well-established Obesity is also associated with chronic low-grade inflammation, insulin resistance, and elevated levels of insulin-like growth factors, all of which can promote cancer development and progression

As with any powerful therapy, there are questions we still need to answer: how these drugs behave over decades, how to protect lean mass at scale, how to dose safely in metabolically healthy individuals, how to separate genuine medical use from cosmetic hype, and how to ensure patients are not starved of protein or muscle