Galukande, M., Wabinga, H., Mirembe, F., Karamagi, C., Asea, A
Following arrival, athymic nude mice were acclimated for a 2-week period in a SPF facility under controlled conditions (22 2 C, 5060% relative humidity) with a standardized 12-h light-dark cycle
That decentralization is what the article credits for fewer bottlenecks
In December 2024, the FDA also resolved its shortage on GLP-1 drugs based on tirzepatide, the active ingredient in Mounjaro and Zepbound
doi: 10.1172/JCI112504 63
"For the newer GLP-1 medications, it would be useful to look at whether there are genetic variants, like the variants in PAM, that explain poor responders to their medications." For now, the biological cause of GLP-1 resistance remains unclear and is likely influenced by multiple factors