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developed a novel reactive matrix, ( E )-2-cyano- N -(2-(2,5-dioxo-2,5-dihydro-1 H -pyrrol-1-yl)ethyl)-3-(4-hydroxyphenyl)acrylamide (CHC-Mal), for the selective detection of free thiol groups in metabolites and proteins by MALDI-MS

has received research support from Pfizer, Sanofi and Regeneron

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