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Structural modifications and advanced formulation strategies have shown great promise in overcoming the inherent limitations of butyrate

It is first identified as a suppressor of murine postnatal alpha fetal protein [20]

These findings underscore both the promise and the challenges of targeting the neddylation pathway for cancer therapy, as well as the need for selective neddylation inhibitors to minimize off-target effects while maximizing therapeutic efficacy

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All uses of GHK-Cu described here are cosmetic in nature