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OSI-906 (linsitinib), a RTKI targeting both IGF-1R and IR, was investigated as a treatment for hormone sensitive breast cancer in combination with endocrine therapy and erlonitib in a phase II clinical trial (NCT01205685)

As research on peptides advances slowly, in the meantime, people are actually converting themselves into the guinea pigs or the lab rats, Taylor says

Concerns about pancreatitis in incretin-based therapy have been raised due to mild elevations in amylase and/or lipase levels (75)

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