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Clinical Benefits and Effects Semaglutide injection provides multiple therapeutic benefits for patients with type 2 diabetes and obesity

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The dosing schedule begins with an initiation dose of 2.5 mg weekly for 4 weeks (not intended for glycaemic control), which is then gradually increased every four weeks to minimise gastrointestinal side effects

Diabetes 61 , 4048 (2012)

[1] However, the clinical significance of these modest elevations remains uncertain, as they occurred in the context of substantial weight loss and improvements in other cardiovascular risk factors, including blood pressure, lipid profiles, and glycemic control in patients with type 2 diabetes