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However, an RCT (n=77) revealed that in relapsing-remitting MS patients, IFN- 1b plus atorvastatin was more likely to cause temporary elevations in liver enzymes than monotherapy, and the combined therapy was not better than monotherapy (Clinicaltrials.gov: NCT00942591) (282)

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In this review, we highlight the emerging evidence linking amino acid metabolic pathwaysparticularly those involving arginine, proline, glycine, and serineto the initiation and progression of pulmonary fibrosis