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Antineoplastic drugs that are known to cause nephrotoxicity include platinum agents (such as cisplatin and carboplatin), antimetabolites (like methotrexate), alkylating agents (including cyclophosphamide and ifosfamide), and anthracyclines (such as doxorubicin and epirubicin)

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By influencing NAD+ levels, we can potentially alter the way these immune cells function, impacting the severity and course of inflammatory responses