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Together, excessive and reduced production of neuro-toxic and -protective kynurenines, respectively, may exacerbate excitotoxicity and neuroinflammation, establishing a feed-forward cycle of KP dysregulation, 5-HT depletion, HPA axis hyperactivity, and increased vulnerability to MDD

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Clinical studies show adequate choline intake lowers liver enzyme levels and improves hepatic insulin sensitivity, both markers of improved liver function and metabolic health

Summary Keywords lactoferrin, bioactive peptide, metabolic syndrome, insulin resistance, hypotension Citation Zong X, Wang Y, Chen Y, Fang P and Zhang Y (2025) Role of lactoferrin and its derived peptides in metabolic syndrome treatment

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